Anti-hyperglycemic Effect of Stephania Glabra Tubers in Alloxan Induced Diabetic Mice
نویسندگان
چکیده
Different doses of ethanolic extract of Stephania glabra tuber were evaluated for antihyperglycemic activity in alloxan induced diabetic mice. The oral administration of 100, 200 and 500 mg/kg body weight showed significant hypoglycemic activity. Glibenclamide (oral hypoglycemic agent, 25 mg/kg, p.o.) has been used as standard.
منابع مشابه
Anti-hyperglycemic Effects of Saffron and its Active Constituents, Crocin and Safranal, in Alloxan-Induced Diabetic Rats
Background: Saffron is the dried stigmata of the flowers of saffron (Crocus sativus L., Iridaceae). Saffron and its major active constituents, crocin (crocetin glycoside), crocetin and safranal, have a variety of pharmacological effects including high antioxidant properties and crocetin has insulin sensitizing effect possibly due to its antioxidant activity. Oral crocin is not absorbed and is h...
متن کاملAnti-hyperglycemic Effects of Vaccinium arctostaphylos L. Fruit and Leaf Extracts in Alloxan-Induced Diabetic Rats
Background: Vaccinium arctostaphylos L. (Caucasian whortleberry) fruit is used as an anti-hyperglycemic agent for treatment of diabetes mellitus. Objective: The effects of whortleberry fruit and leaf extracts on the blood levels of fasting glucose, HbA1c (glycosylated hemoglobin), insulin, creatinine and liver enzymes SGOT and SGPT in alloxan-diabetic rats as well as LD50s of the extracts in ...
متن کاملEffects of Turnera ulmifolia (Linn.) Leaves on Blood Glucose Level in Normal and Alloxan-Induced Diabetic Rats
The methanolic extract of leaves of Turnera ulmifolia L was evaluated for its effect on blood glucose in alloxan-induced diabetic and euglycemic rats. The extract were administered at three doses of 100, 200 and 400 mg/kg, p.o. Glibenclamide (10 mg/kg, p.o.) was used as standard for control group. In euglycemic rat, extract were administered at three doses of 100, 200 and 400 mg/kg, p.o. Extr...
متن کاملIn vitro free radical scavenging and anti-hyperglycemic activities of Achyranthes aspera extract in alloxan-induced diabetic mice.
Medicinal plants have played an important role in the treatment and prevention of diseases since ancient times. They are also potential sources of nutrients and drugs. This study evaluated Achyranthes aspera ethanolic extracts for their in vitro antioxidant activity and anti-hyperglycemic effects on alloxan-induced diabetic mice. Diabetes was induced in Swiss albino mice through intra-peritonea...
متن کاملBiol. Pharm. Bull. 30(11) 2079—2083 (2007)
tion in Kampo medicine and consists of Stephania tetrandra Radix (Stephania), Astragalus membranaceus BUNGE Radix (Astragali), Atractylodes Lancea Rhizoma, Glycyrrhizae Radix, Zingiberis Rhizoma and Zizyphi Fructus. Boi-ogi-to has long been used clinically in the treatment of arthritis and edema in China and Japan. It also improves abnormal glucose and lipid metabolism in obese diabetic patient...
متن کامل